After One Piece Season 1 premiered on Netflix, Jamie Lee Curtis was fan-cast as Dr. Kureha, which she eagerly embraced before promising to lobby for the part after the 2023 actors' strike ended. But as revealed a few weeks ago, Curtis didn't land the role of Dr. Kureha and she won't appear in Season 2 over scheduling issues. Instead, Katey Sagal has been cast in the part for next season.

Audiences are likely to recognize Sagal for her time on FX's Sons of Anarchy or her roles on Futurama and The Conners. She first came to fame in Married with Children, an early Fox sitcom. Sagal's character, Dr. Kureha, is the leader of the Isshi-100 Drum Island and an ally of the Straw Hat Pirates.

Additionally, Presumed Innocent co-star Mark Harelik is joining the cast as Dr. Hiriluk, whose last name is almost a homonym for the actor's. Hiriluk is also a doctor on Drum Island. In his life prior to coming to the island, Hirluk was a thief.