The Nemesis in Resident Evil 3 Remake is nigh unstoppable, and you'll spend a lot of the game fleeing as he stalks you relentlessly. Like Mr. X in Resident Evil 2 Remake, you can't kill him--but you can slow him down, if you're willing to fight. Running away is usually the better option, though, and it can be tempting to just bail on the Nemesis and conserve your ammo. But there are two moments in Resident Evil 3 Remake when you want to stop and hold your ground, even though you don't have to, in order to snag some big rewards.

As in the original Resident Evil 3, if you hit the Nemesis with enough firepower or explosives as he's sprinting after you through the streets of Raccoon City, you can knock him out for a few moments. Do that, and he'll drop a Supply Case. There are two important handgun upgrades you can only get by fighting the Nemesis at key moments, and if you miss your chance at them, you'll never receive those items. Without them, you can't complete one of the bonus Record objectives for Resident Evil 3 Remake's post-game; you'll also want all the firepower you can get, especially on RE3 Remake's tougher difficulties. Here's what you need to beat the Nemesis, what you'll get for doing it, and most importantly, when to take him on.

If you need more Resident Evil 3 content, we've got you covered. Check out our full Resident Evil 3 Remake walkthrough for help on everything. We've also got a complete list of Resident Evil 3 lockpick locks, as well as safe locations and codes, a guide to finding every Hip Pouch, a full rundown of weapon upgrades and where to find them, and a guide to finding the jewels for the Kite Road Railway Monument puzzle.