Smite 2 is set to revamp the action MOBA's pantheon, with overhauled visuals and revamped Gods. The sequel has been newly constructed in Unreal Engine 5.

The sequel promises a cleaner user interface with easier-to-parse spell effects. Each God's abilities have also gotten changes, and some Gods like Ymir have new physics-based powers. The game adds two power sources, Strength and Intelligence, to further distinguish each God's abilities. At first glance, the game appears to play much as the first one did.

Smite 2 moves to a new backend, enabling cross-play, improved matchmaking, and a reworking of the ranking system. The Relic and Items systems have also been totally overhauled to be more accessible to new players.